Mito Plot

The Mito Plot Chart is a specialized visualization based on mitochondrial DNA (mtDNA) studies. It displays the basic structure of mitochondrial DNA, divided into different segments. Each segment produces an RNA type protein essential during the cellular respiration cycle.

  • The chart segments are colored based on RNA type.

  • Mitochondrial DNA has two strands:

    • H-Strand (Heavy Strand): Guanine-rich, oriented outwards.

    • L-Strand (Light Strand): Cytosine-rich, oriented inwards.

This allows medical experts and researchers to visualize mitochondrial damage, protein encoding, and nucleotide strand orientation in a clear graphical form.

Best Situations to Use

Use a Mito Plot chart when:

  • Visualizing mitochondrial DNA structure and RNA protein-coding regions.

  • Analyzing damage or mutations in specific mtDNA segments.

  • Differentiating between heavy (H-strand) and light (L-strand) nucleotide strands.

  • Studying genomic data in a visual, strand-oriented representation.

Examples:

  • Medical research to visualize individual-specific mtDNA damage.

  • Identifying strand orientation (H vs. L) mutations.

  • Genetic analysis in clinical or laboratory studies.

Properties

General

  • Component Name – Auto-generated unique identifier.

  • Position (Left, Top) – Placement on the canvas.

  • Height / Width – Chart dimensions.

  • Initial Visibility – Show/hide chart on load.

  • Max Button – Enable maximize view.

  • Series Colors – Define segment colors by RNA type.

  • Chart Alignment – Align chart (Left, Center, Right).

Tooltip

  • Show/hide tooltips with series descriptions.

  • Supported types: None, Custom.

  • Customize tooltip background, opacity, border color, font size, and width.

  • Control decimal precision for numeric data.

Background & Styling

  • Gradient rotation, opacity, and multi-color customization.

  • Borders (color, radius, width).

  • Shadows with adjustable color and transparency.

Title & Subtitle

  • Show/hide title and subtitle.

  • Customize text (font color, size, style, weight, alignment, decoration).

  • Option to use dataset descriptions as titles.

Export Options

  • Enable context menu for export.

  • Supported formats: Excel, CSV, JPEG, PNG, PPT, PDF, Print.

  • Customize export heading, subheading, and file name.

  • Define global export type (Screenshot or Tabular).

Example Use Cases

  • Medical Genetics: Highlight mutations in mtDNA affecting respiratory chain proteins.

  • Molecular Biology: Show RNA type coding in mitochondrial genome regions.

  • Clinical Research: Compare damaged vs. normal mitochondrial strands.

  • Education: Demonstrate H-strand vs. L-strand differences in DNA structure.

Sample Data Setup:

  • Category Field: Patient_seq (DNA sequence ID).

  • RNA Type Field: Color_rnaType (defines RNA coding type).

  • Orientation Field: Orientation (H-strand or L-strand).

  • Start / Stop Fields: Define nucleotide start and stop positions.

  • Marker Field: dataLabel_pos (labels or markers for segments).

14KB
Sample Data_Mito chart.xlsx
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⚠️ Note:

  • H-Strand segments are oriented outward.

  • L-Strand segments are oriented inward.

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